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Identification of a promoter element which participates in cAMP-stimulated expression of human insulin-like growth factor-binding protein
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We have noted that two oxidized metabolites activate either receptor with apparent EC 50 values two orders of magnitude below that seen for DHEA, depending upon the cell morning sex and testosterone in Evansville in which the experiments are performed data not shown.
To date, activation of the peroxisome proliferators activated receptor alpha, pregnane X receptor, and estrogen receptor by DHEA and its metabolites have been demonstrated. No doctor or consultation visit is needed. Direct analysis of dehydroisoandrosterone in plasma.
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Environmental phthalate monoesters activate pregnane X receptor-mediated transcription.