Polygenic sex determination system in zebra fish research in Illinois

Several lines were split into sub-lines that were later split further depending on the sex ratios resulting from the multifactorial crosses. Biology References 1 Miller, G. Westerfield M. The main characteristics of PSD observed in zebrafish include: i cumulative effect of multiple genes on SD; ii wide ranging familial sex ratios including severely biased lines that are stable in repeated crosses; iii strong influence from parental genotypes and iv a large number of expected sexual genotypes among the gametes, not just two as in CSD species.

Closed-loop control of zebrafish response using a bioinspired robotic-fish in a preference test.

The control family D4F3 had a mass cross performed in the F 2 generation without selection. To ask whether rearing density influences sex determination in zebrafish, we raised groups of zebrafish at three different densities from 5 dpf to adulthood and assayed the sex ratios of the resulting adults.

We continued our investigation for sex-linked differences at the genome level by aCGH. USAE—E Johnson, S. Pharmaceutical innovation in the 21st century: new drug approvals in the first decade, —

Polygenic sex determination system in zebra fish research in Illinois этом

Norton W, Bally-Cuif L. None of them showed sex-linked inheritance pattern. DeFalco T, Capel B. Identification of large-scale human-specific copy number polygenic sex determination system in zebra fish research in Illinois by inter-species array comparative genomic hybridization.

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The zebrafish as a model organism for the study of apoptosis. Figure S3 Sex-linked FluoMEP markers obtained by bulk segregant analysis performed on pooled male and female samples of guppy Poecilia reticulata. Based on our data and the recent aforementioned association study [78]we propose that the number of genes contributing to the sex determination process might be far more than just a handful.

  • Despite the popularity of zebrafish as a research model, its sex determination SD mechanism is still unknown. Most cytogenetic studies failed to find dimorphic sex chromosomes and no primary sex determining switch has been identified even though the assembly of zebrafish genome sequence is near to completion and a high resolution genetic map is available.
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Studies on various teleost species, including zebrafish, showed that elevated water temperature affected different gonadal processes, including apoptosis, estrogen biosynthesis and germ cell meiosis [ 45 , 47 , 48 ]. Phylogenetic relationships of Danio within the order Cypriniformes: a framework for comparative and evolutionary studies of a model species.

Neurobiology of rodent self-grooming and its value for translational neuroscience. Female-biased offspring. For simplicity, it is assumed that i for every locus there is a strong larger shape and upper case letter and weak smaller shape and lower case letter effect allele; ii the effect of the four strong alleles are equal and the same is true for the four weak alleles at a lower level and iii the four products do not exert any direct effect on the functions of each other.

Based on the sex ratio of the offspring we have chosen five lines to be used for selection against males or females Fig.

Polygenic sex determination system in zebra fish research in Illinois

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  • zebrafish has a polygenic sex determination system. Citation: Liew WC, Bartfai R, Lim Z, Sreenivasan R, Siegfried KR, et al. () Polyge nic Sex Determination System in Zebrafish. PLoS ONE 7(4. In order to elucidate whether CSD is the main sex determination system in zebrafish, the sex ratios of 62 families were analyzed. The percentage of males among the families analyzed ranged from % to % with median of 51% (std. dev. ±%; Fig. 1). Such a wide-ranging sex ratio among the families would be highly unusual for a Cited by:
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  • Polygenic Sex Determination System in Zebrafish Woei Chang Liew, Richard Bartfai, Zijie Lim, Rajini Sreenivasan, Kellee R. Siegfried, Laszlo Orban Abstract: BackgroundDespite the popularity of zebrafish as a research model, its sex determination (SD) mechanism is still unknown. Earlier, others have indicated the possibility of a polygenic sex determination system for zebrafish based on a single set of experiment each (see e.g. [94] & [78]). Our study adds data obtained by four different methods that all point to a polygenic sex determination system, creating a tipping point in Cited by:
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  • Despite the popularity of zebrafish as a research model, its sex determination (​SD) mechanism is still unknown. Most cytogenetic studies failed to. Most cytogenetic studies failed to find dimorphic sex chromosomes and no primary sex determining switch has been identified even though the.
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  • polygenic sex determination, sex chromosome, gonad differentiation, teleost, fish, Danio rerio Studies on various teleost species, including zebrafish, showed that Inferring the type of sex chromosomal system by progeny sex ratio as a result of Il cariotipo di alcune specie di Cyprinidae, Centrarchidae. Polygenic Sex Determination System in Zebrafish Background Despite the popularity of zebrafish as a research model, its sex determination (SD) mechanism.
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